Comparison of a morning polypill, evening polypill and individual pills on LDL-cholesterol, ambulatory blood pressure and adherence in high-risk patients; a randomized crossover trial.

@article{Lafeber2015ComparisonOA,
  title={Comparison of a morning polypill, evening polypill and individual pills on LDL-cholesterol, ambulatory blood pressure and adherence in high-risk patients; a randomized crossover trial.},
  author={Melvin Lafeber and Diederick E Grobbee and Ilse M. Schrover and Simon Thom and Ruth Webster and Anthony Rodgers and Frank L. J. Visseren and M. L. Bots and Wilko Spiering},
  journal={International journal of cardiology},
  year={2015},
  volume={181},
  pages={
          193-9
        }
}
  • Melvin Lafeber, Diederick E Grobbee, +6 authors Wilko Spiering
  • Published in
    International journal of…
    2015
  • Medicine
  • AIMS Cardiovascular polypills are a novel strategy in the prevention of cardiovascular disease. Based on considerations about the effectiveness, the individual pills of a polypill are taken at different times of the day. This study aimed therefore to compare the use of a polypill in the morning, in the evening or the individual components taken at their usual times on cardiovascular risk factors and patient acceptability. METHODS The study was a randomized three-period crossover trial… CONTINUE READING

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