Comparison of Two High-Throughput Assays for Quantification of Adenovirus Type 5 Neutralizing Antibodies in a Population of Donors in China

@inproceedings{Liu2012ComparisonOT,
  title={Comparison of Two High-Throughput Assays for Quantification of Adenovirus Type 5 Neutralizing Antibodies in a Population of Donors in China},
  author={Qiang Liu and Jianhui Nie and Weijin Huang and Shufang Meng and Baozhu Yuan and Dongying Gao and Xuemei Xu and Youchun Wang},
  booktitle={PloS one},
  year={2012}
}
BACKGROUND The presence of various levels of Adenovirus serotype 5 neutralizing antibodies (Ad5NAb) is thought to contribute to the inconsistent clinical results obtained from vaccination and gene therapy studies. Currently, two platforms based on high-throughput technology are available for Ad5NAb quantification, chemiluminescence- and fluorescence-based assays. The aim of this study was to compare the results of two assays in the seroepidemiology of Ad5NAb in a local population of donors… CONTINUE READING

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