Comparison of Tissue Factor Pathway in Human Umbilical Vein and Adult Saphenous Vein Endothelial Cells: Implications for Newborn Hemostasis and for Laboratory Models of Endothelial Cell Function

In this work we have undertaken a comparative study of human umbilical vein endothelial cells (HUVECs) and human saphenous vein endothelial cells (HSVECs) with respect to functional and antigenic tissue factor (TF), tissue factor pathway inhibitor (TFPI), and TF mRNA. Monolayers of each cell type (passage 2, except where specified) were grown to confluence… (More)