Comparison of Spectinomycin Hydrochloride and Aqueous Procaine Penicillin G in the Treatment of Uncomplicated Gonorrhea

@article{Duani1974ComparisonOS,
  title={Comparison of Spectinomycin Hydrochloride and Aqueous Procaine Penicillin G in the Treatment of Uncomplicated Gonorrhea},
  author={A Duan{\'c}i{\'c} and Nicholas J. Fiumara and Seymour Alpert and Young Ho Lee and Phillip I Tarr and Bernard Rosner and William M. McCormack},
  journal={Antimicrobial agents and chemotherapy},
  year={1974},
  volume={6 4},
  pages={
          512-5
        }
}
Men and women with uncomplicated gonorrhea were randomly assigned to receive aqueous procaine penicillin G (2,400,000 U for men; 2,400,000 U daily for 2 days for women) or spectinomycin hydrochloride (2.0 g for men; 4.0 g for women). Among men who returned for post-treatment evaluation within 10 days, treatment failures were noted among 16 (20.3%) of 79 men who received penicillin and 8 (9.5%) of 84 men who received spectinomycin (P < 0.1). Similarly, 6 (13.3%) of 45 women who received… CONTINUE READING

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