Comparison of Retinal Nerve Fiber Layer Thinning and Retinal Ganglion Cell Loss After Optic Nerve Transection in Adult Albino Rats.

@article{Rovere2015ComparisonOR,
  title={Comparison of Retinal Nerve Fiber Layer Thinning and Retinal Ganglion Cell Loss After Optic Nerve Transection in Adult Albino Rats.},
  author={Giuseppe Rovere and Francisco M Nadal-Nicol{\'a}s and Marta Agudo-Barriuso and Paloma Sobrado-Calvo and Leticia Nieto-L{\'o}pez and Carlo Nucci and Mar{\'i}a Paz Villegas-P{\'e}rez and Manuel Vidal-Sanz},
  journal={Investigative ophthalmology & visual science},
  year={2015},
  volume={56 8},
  pages={
          4487-98
        }
}
PURPOSE We compared the time-course and magnitude of retinal nerve fiber layer (RNFL) thinning with that of retinal ganglion cell (RGC) loss after intraorbital optic nerve transection (IONT) in adult rats. METHODS At 3, 7, 12, or 21 days, or 1, 2, or 4 months after ONT, the retinas were imaged with spectral-domain optical coherence tomography (SD-OCT) using the circular-peripapillary scan and volume scan raster pattern (61 horizontal sections equally spaced) both centered in the optic nerve… CONTINUE READING

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