Comparison of RNA-Seq and Microarray in Transcriptome Profiling of Activated T Cells

@inproceedings{Zhao2014ComparisonOR,
  title={Comparison of RNA-Seq and Microarray in Transcriptome Profiling of Activated T Cells},
  author={Shanrong Zhao and Wai-Ping Fung-Leung and Anton Bittner and Karen Ngo and Xuejun Liu},
  booktitle={PloS one},
  year={2014}
}
To demonstrate the benefits of RNA-Seq over microarray in transcriptome profiling, both RNA-Seq and microarray analyses were performed on RNA samples from a human T cell activation experiment. In contrast to other reports, our analyses focused on the difference, rather than similarity, between RNA-Seq and microarray technologies in transcriptome profiling. A comparison of data sets derived from RNA-Seq and Affymetrix platforms using the same set of samples showed a high correlation between gene… CONTINUE READING

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