Comparison of RNA, single‐stranded DNA and double‐stranded DNA behavior during capillary electrophoresis in semidilute polymer solutions

@article{Todorov2002ComparisonOR,
  title={Comparison of RNA, single‐stranded DNA and double‐stranded DNA behavior during capillary electrophoresis in semidilute polymer solutions},
  author={Todor I. Todorov and Michael D. Morris},
  journal={ELECTROPHORESIS},
  year={2002},
  volume={23}
}
We present a study of the separation of RNA, single‐stranded DNA (ssDNA) and double‐stranded DNA (dsDNA) in semidilute linear hydroxyethylcellulose (HEC) solution. Our results strive to provide a better understanding of the mechanisms of nucleic acid migration during electrophoresis in polymer solutions under native and denaturing conditions. From a study of the dependence of mobility on chain length and applied electric field, we found that RNA and ssDNA show better separation and higher… 

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