Comparison of Prostaglandin E1 and Sildenafil Citrate Administration on Skin Flap Survival in Rats


BACKGROUND Alprostadil and sildenafil are known vasodilators used independently to improve flap survival in animal models. In this study, we investigate whether these agents act synergistically to decrease flap necrosis in rat models. METHODS After acclimation period, 4 groups of 10 male white rats were given a modified McFarlane skin flap. The… (More)
DOI: 10.7181/acfs.2015.16.2.73

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