Comparison of PCR with direct examination of bone marrow aspiration, myeloculture, and serology for diagnosis of visceral Leishmaniasis in immunocompromised patients.

@article{Piarroux1994ComparisonOP,
  title={Comparison of PCR with direct examination of bone marrow aspiration, myeloculture, and serology for diagnosis of visceral Leishmaniasis in immunocompromised patients.},
  author={Renaud Piarroux and Françoise Gambarelli and Henri Dumon and Michel Font{\'e}s and S R Dunan and C. Jinitha Mary and B. Toga and M. C. Quilici},
  journal={Journal of clinical microbiology},
  year={1994},
  volume={32 3},
  pages={746-9}
}
A PCR assay amplifying a repeated sequence from the Leishmania infantum genome was compared with direct examination of bone marrow aspirate, myeloculture, and serology for the diagnosis of visceral leishmaniasis in immunocompromised patients. Of 73 patients living in an area endemic for leishmaniasis and where visceral leishmaniasis was suspected by physicians, only 10 had an indisputable diagnosis of visceral leishmaniasis. None of the diagnostic tests performed in the study achieved 100… CONTINUE READING