Comparison of PCR and other diagnostic techniques for detection of Helicobacter pylori infection in dyspeptic patients.

@article{Weiss1994ComparisonOP,
  title={Comparison of PCR and other diagnostic techniques for detection of Helicobacter pylori infection in dyspeptic patients.},
  author={Joseph B. Weiss and J J Mecca and Edson Pedro da Silva and David Gassner},
  journal={Journal of clinical microbiology},
  year={1994},
  volume={32 7},
  pages={1663-8}
}
A sensitive and specific PCR-based assay to detect the Helicobacter pylori 16S rRNA gene present in formalin-fixed paraffin-embedded gastric biopsy specimens has been developed. A total of 95 patients with dyspepsia were evaluated for the presence of chronic active gastritis and an infection with H. pylori through the use of diagnostic assays based on biopsy specimens and serology. The "gold standard" for the presence of the bacteria was direct detection in histological sections of biopsy… CONTINUE READING
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Helicobacterpylori: current status

  • D. Y. Graham, M. F. Guo
  • Gastroenterology
  • 1993

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