Comparison of PCR-RFLP and Genescan-based genotyping for analyzing infection dynamics of Plasmodium falciparum.

@article{Falk2006ComparisonOP,
  title={Comparison of PCR-RFLP and Genescan-based genotyping for analyzing infection dynamics of Plasmodium falciparum.},
  author={Nicole Falk and Nicolas Maire and Wilson Sama and Seth Owusu-Agyei and Torben Smith and H. Beck and Ingrid Felger},
  journal={The American journal of tropical medicine and hygiene},
  year={2006},
  volume={74 6},
  pages={944-50}
}
Parameters describing the infection dynamics of Plasmodium falciparum are important determinants of the potential impact of interventions and are potential outcome measurements for malaria intervention trials. Low parasite densities, periodic sequestration of parasites, and the presence of multiple concurrent infections make it essential to use molecular techniques to estimate the force of infection and duration of infections in endemic areas. We now compare two approaches for tracking… CONTINUE READING

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