Comparison of Nramp 1 Gene Polymorphism among TB Health Care Workers and Recently Infected Cases ; Assessment of Host Susceptibility

@inproceedings{Farnia2008ComparisonON,
  title={Comparison of Nramp 1 Gene Polymorphism among TB Health Care Workers and Recently Infected Cases ; Assessment of Host Susceptibility},
  author={Parisa Farnia and Omid Pajand and Saber Anoosheh and Payam Tabarsi and Mehdi Kazampour Dizaji and Forozan Mohammadi and Mohammad Hadi Varahram and Parvaneh Baghaei and Moslem Bahadori and Mohammad Reza Masjedi and Ali Akbar Velayati},
  year={2008}
}
Background: A link between polymorphisms in the natural resistance –associated macrophage protein gene 1 (Nramp) and susceptibility to tuberculosis (TB) has been demonstrated worldwide. This study aimed to investigate the Nramp1 gene variants among workers exposed to TB bacilli (1-2 hours per day for 1 to 20 years) who did not develop the diseases with those who developed the disease through recent transmission. Materials and Methods: The polymorphism of Nramp1 at INT4, D543 and 3'UTR was… CONTINUE READING