Comparison of Morphological and Functional Meibomian Gland Characteristics Between Daily Contact Lens Wearers and Nonwearers.

@article{Machaliska2015ComparisonOM,
  title={Comparison of Morphological and Functional Meibomian Gland Characteristics Between Daily Contact Lens Wearers and Nonwearers.},
  author={Anna Machalińska and Aleksandra Zakrzewska and Bogdan Adamek and Krzysztof Safranow and Barbara Wiszniewska and Mirosław Parafiniuk and Bogusław Machaliński},
  journal={Cornea},
  year={2015},
  volume={34 9},
  pages={1098-104}
}
PURPOSE The aim of the study was to investigate the relationship between daily soft contact lens (CL) wear and various signs of ocular involvement. We focused on comprehensive meibomian gland (MG) evaluation, including both functional and morphological parameters of the MGs. METHODS The ocular surface and MG characteristics were evaluated in 41 daily soft CL users and 31 age-matched non-lens wearers. We analyzed the MG function (meibum quality and meibum expressibility) and morphology… CONTINUE READING

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CL use was associated with abnormal meibum quality [ higher meibum quality score , odds ratio ( OR ) = 2.7 , 95% confidence interval ( CI ) , 1.3 - 5.6 , P = 0.0057 ] , more frequent bulbar ( OR = 3.6 , 95% CI , 1.5 - 8.2 , P = 0.0028 ) and palpebral ( OR = 2.4 , 95% CI , 1.1 - 5.1 , P = 0.028 ) conjunctival hyperemia , lid margin telangiectasia ( OR = 6.0 , 95% CI , 2.4 - 14.6 , P < 0.00001 ) , rounding ( OR = 9.3 , 95% CI , 1.1 - 81.0 , P = 0.04 ) , notching ( OR = 3.9 , 95% CI , 1.2 - 12.4 , P = 0.019 ) , hyperemia ( OR = 4.3 , 95% CI , 1.3 - 14.1 , P = 0.015 ) of the posterior lid margin , orifice plugging ( OR = 4.8 , 95% CI , 1.3 - 17.1 , P = 0.015 ) , and retroplacement ( OR = 0.8 , 95% CI , 0.4 - 1.9 , P = 0.037 ) after adjustment for age and sex in a logistic regression model . Lid margin abnormality and meibum quality scores strongly positively correlated with the duration of CL wear .
CL use was associated with abnormal meibum quality [ higher meibum quality score , odds ratio ( OR ) = 2.7 , 95% confidence interval ( CI ) , 1.3 - 5.6 , P = 0.0057 ] , more frequent bulbar ( OR = 3.6 , 95% CI , 1.5 - 8.2 , P = 0.0028 ) and palpebral ( OR = 2.4 , 95% CI , 1.1 - 5.1 , P = 0.028 ) conjunctival hyperemia , lid margin telangiectasia ( OR = 6.0 , 95% CI , 2.4 - 14.6 , P < 0.00001 ) , rounding ( OR = 9.3 , 95% CI , 1.1 - 81.0 , P = 0.04 ) , notching ( OR = 3.9 , 95% CI , 1.2 - 12.4 , P = 0.019 ) , hyperemia ( OR = 4.3 , 95% CI , 1.3 - 14.1 , P = 0.015 ) of the posterior lid margin , orifice plugging ( OR = 4.8 , 95% CI , 1.3 - 17.1 , P = 0.015 ) , and retroplacement ( OR = 0.8 , 95% CI , 0.4 - 1.9 , P = 0.037 ) after adjustment for age and sex in a logistic regression model . Lid margin abnormality and meibum quality scores strongly positively correlated with the duration of CL wear .
CL use was associated with abnormal meibum quality [ higher meibum quality score , odds ratio ( OR ) = 2.7 , 95% confidence interval ( CI ) , 1.3 - 5.6 , P = 0.0057 ] , more frequent bulbar ( OR = 3.6 , 95% CI , 1.5 - 8.2 , P = 0.0028 ) and palpebral ( OR = 2.4 , 95% CI , 1.1 - 5.1 , P = 0.028 ) conjunctival hyperemia , lid margin telangiectasia ( OR = 6.0 , 95% CI , 2.4 - 14.6 , P < 0.00001 ) , rounding ( OR = 9.3 , 95% CI , 1.1 - 81.0 , P = 0.04 ) , notching ( OR = 3.9 , 95% CI , 1.2 - 12.4 , P = 0.019 ) , hyperemia ( OR = 4.3 , 95% CI , 1.3 - 14.1 , P = 0.015 ) of the posterior lid margin , orifice plugging ( OR = 4.8 , 95% CI , 1.3 - 17.1 , P = 0.015 ) , and retroplacement ( OR = 0.8 , 95% CI , 0.4 - 1.9 , P = 0.037 ) after adjustment for age and sex in a logistic regression model . Lid margin abnormality and meibum quality scores strongly positively correlated with the duration of CL wear .
CL use was associated with abnormal meibum quality [ higher meibum quality score , odds ratio ( OR ) = 2.7 , 95% confidence interval ( CI ) , 1.3 - 5.6 , P = 0.0057 ] , more frequent bulbar ( OR = 3.6 , 95% CI , 1.5 - 8.2 , P = 0.0028 ) and palpebral ( OR = 2.4 , 95% CI , 1.1 - 5.1 , P = 0.028 ) conjunctival hyperemia , lid margin telangiectasia ( OR = 6.0 , 95% CI , 2.4 - 14.6 , P < 0.00001 ) , rounding ( OR = 9.3 , 95% CI , 1.1 - 81.0 , P = 0.04 ) , notching ( OR = 3.9 , 95% CI , 1.2 - 12.4 , P = 0.019 ) , hyperemia ( OR = 4.3 , 95% CI , 1.3 - 14.1 , P = 0.015 ) of the posterior lid margin , orifice plugging ( OR = 4.8 , 95% CI , 1.3 - 17.1 , P = 0.015 ) , and retroplacement ( OR = 0.8 , 95% CI , 0.4 - 1.9 , P = 0.037 ) after adjustment for age and sex in a logistic regression model . Lid margin abnormality and meibum quality scores strongly positively correlated with the duration of CL wear .
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