Comparison of Low - Flow and Normal - Flow Patients Low Flow Normal Flow P Value

Abstract

Aortic valve replacement (AVR) is indicated for patients with severe aortic stenosis (AS) associated with either symptoms or left ventricular (LV) dysfunction. Severe AS is generally defined as an aortic valve area ≤1.0 cm and a mean transvalvular gradient of ≥40 mm Hg. However, many patients with symptomatic and severe AS may have lower gradients resulting from LV systolic dysfunction (so-called low flow [LF], low ejection fraction [LEF]), high afterload with pronounced LV concentric remodeling (paradoxical LF, normal ejection fraction [NEF]), and from errors or assumptions inherent in the measurement of gradient and valve area. These patients have a prognosis similar to or worse than that for patients with classic AS, both with and without surgery. However, little is known about the prognostic value of LF independently of gradient and EF and its treatment.

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Cite this paper

@inproceedings{Herrmann2013ComparisonOL, title={Comparison of Low - Flow and Normal - Flow Patients Low Flow Normal Flow P Value}, author={Howard C Herrmann and Philippe Pibarot and William J. Stewart and Samir R Kapadia and Emin Murat Tuzcu and Vasilis C . Babaliaros and Vinod H . Thourani and Wilson Y . Szeto and Joseph E . Bavaria and Susheel K . Kodali and Rebecca T . Hahn and Mathew Russell Williams and David C. Miller and Pamela Douglas and Martin B . Leon}, year={2013} }