Comparison of IgG antibody levels to Clostridium botulinum antigens between euthanased and surviving cases of chronic grass sickness.

@article{Nunn2007ComparisonOI,
  title={Comparison of IgG antibody levels to Clostridium botulinum antigens between euthanased and surviving cases of chronic grass sickness.},
  author={F G Nunn and R S Pirie and B. C. McGorum and Ulrich Wernery and Ian R. Poxton},
  journal={Research in veterinary science},
  year={2007},
  volume={83 1},
  pages={
          82-4
        }
}
Serum from 12 horses suffering from chronic grass sickness (CGS) were assayed for IgG antibodies against botulinum neurotoxins C and D (BoNT/C and BoNT/D) and to a surface antigen extract of a neurotoxin negative strain of Clostridium botulinum type C. Collectively, the six surviving CGS cases demonstrated significantly higher initial IgG levels (P=0.05) against surface antigens than the six that were subsequently euthanased. The surviving animals also demonstrated higher initial IgG levels… CONTINUE READING