Comparison of H2O2-induced vasoconstriction in the abdominal aorta and mesenteric artery of the mouse.

@article{Ardanaz2007ComparisonOH,
  title={Comparison of H2O2-induced vasoconstriction in the abdominal aorta and mesenteric artery of the mouse.},
  author={Noelia Ardanaz and William H. Beierwaltes and Patrick J Pagano},
  journal={Vascular pharmacology},
  year={2007},
  volume={47 5-6},
  pages={
          288-94
        }
}
Hydrogen peroxide (H(2)O(2)) is generally perceived as an arterial vasodilator. Due to the emerging importance of H(2)O(2) as a possible vasoconstrictor, we examined whether H(2)O(2) constricts both the abdominal aorta and superior mesenteric artery and postulated that H(2)O(2) is a ubiquitous constrictor of quiescent mouse arteries. Moreover, we postulated that KCl depolarization discloses and/or exaggerates H(2)O(2)-induced constriction. Under quiescent conditions, H(2)O(2) constricted the… CONTINUE READING
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