Comparison of Fibroblast Growth-factor Receptor Gene Alterations at the DNA versus Messenger RNA Level in Advanced Urothelial Cancer: Insights for Clinical Research.

@article{Necchi2017ComparisonOF,
  title={Comparison of Fibroblast Growth-factor Receptor Gene Alterations at the DNA versus Messenger RNA Level in Advanced Urothelial Cancer: Insights for Clinical Research.},
  author={Andrea Necchi and Daniele Raggi and Chiara Costanza Volpi and Patrizia Giannatempo and Maurizio Colecchia and Annunziata Gloghini},
  journal={European urology focus},
  year={2017}
}
Pan-fibroblast growth-factor receptor (FGFR) inhibitors hold promise in FGFR-altered patients, but such alterations are rare in advanced urothelial carcinoma. In order to assess whether we may increase the number of eligible patients by using different molecular techniques for detecting alterations, we pooled the results of the centralised FGFR mutation… CONTINUE READING