Comparison of Expression of Secondary Metabolite Biosynthesis Cluster Genes in Aspergillus flavus, A. parasiticus, and A. oryzae

@inproceedings{Ehrlich2014ComparisonOE,
  title={Comparison of Expression of Secondary Metabolite Biosynthesis Cluster Genes in Aspergillus flavus, A. parasiticus, and A. oryzae},
  author={Kenneth C. Ehrlich and Brian M. Mack},
  booktitle={Toxins},
  year={2014}
}
  • Kenneth C. Ehrlich, Brian M. Mack
  • Published in Toxins 2014
  • Biology, Medicine
  • Fifty six secondary metabolite biosynthesis gene clusters are predicted to be in the Aspergillus flavus genome. In spite of this, the biosyntheses of only seven metabolites, including the aflatoxins, kojic acid, cyclopiazonic acid and aflatrem, have been assigned to a particular gene cluster. We used RNA-seq to compare expression of secondary metabolite genes in gene clusters for the closely related fungi A. parasiticus, A. oryzae, and A. flavus S and L sclerotial morphotypes. The data help to… CONTINUE READING

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