Comparison of European and U.S. results for cephalosporin versus penicillin treatment of group A streptococcal tonsillopharyngitis

@article{Pichichero2006ComparisonOE,
  title={Comparison of European and U.S. results for cephalosporin versus penicillin treatment of group A streptococcal tonsillopharyngitis},
  author={M E Pichichero and Janet R. Casey},
  journal={European Journal of Clinical Microbiology and Infectious Diseases},
  year={2006},
  volume={25},
  pages={354-364}
}
  • M. Pichichero, J. Casey
  • Published 2006
  • Medicine
  • European Journal of Clinical Microbiology and Infectious Diseases
The outcome of cephalosporin versus penicillin treatment of group A streptococcal tonsillopharyngitis may differ between Europe and the USA. In the present study, Medline, Embase, reference lists, and abstract searches were used to identify randomized, controlled trials of cephalosporin versus penicillin treatment of group A streptococcal (GAS) tonsillopharyngitis. The outcomes of interest were bacteriologic and clinical cure rates from investigations conducted in Europe versus those conducted… Expand
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22 Citations
Background Citations
6
Methods Citations
1
Results Citations
2

22 Citations

Citation Type

Citation Type

The Importance of Bacteriologic Eradication in the Treatment of Group A Streptococcal Tonsillopharyngitis
TLDR
The evidence base supporting the selection of cephalosporins in preference to penicillin for treatment of group A β-hemolytic streptococci tonsillopharyngitis is very strong (type A), and these agents have a better tolerability and adherence profile. Expand
The evidence base for cephalosporin superiority over penicillin in streptococcal pharyngitis.
TLDR
Evidence supporting the use of cephalosporins as a first choice of treatment for many patients with GABHS pharyngitis is examined. Expand
Evaluation of short-term clinical efficacy of 3-day therapy with azithromycin in comparison with 5-day cefcapene-pivoxyl for acute streptococcal tonsillopharyngitis in primary care
  • T. Koga, T. Rikimaru, +4 authors K. Matsuo
  • Medicine
  • Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy
  • 2011
TLDR
The clinical efficacy of a 3-day course with AZM was comparable with that of a 5- day course of CFPN-PI for GAS tonsillopharyngitis, and there was no significant difference in clinical efficacy between the two treatments. Expand
Bacterial eradication rates with shortened courses of 2nd- and 3rd-generation cephalosporins versus 10 days of penicillin for treatment of group A streptococcal tonsillopharyngitis in adults.
TLDR
In a meta-analysis of 5 randomized controlled trials involving 1030 adults, the likelihood of bacteriologic eradication in the treatment of group A beta-hemolytic streptococcal (GAS) tonsillopharyngitis with 5 days of select cephalosporins was noninferior to 10 days of penicillin. Expand
Five-day oral cefditoren pivoxil versus 10-day oral amoxicillin for pediatric group A streptococcal pharyngotonsillitis
TLDR
Because the efficacy for pediatric group A streptococcus pharyngotonsillitis was similar between oral cefditoren-pivoxil for 5 days and amoxicillin for 10 days, the shorter treatment period may make the former regimen preferable. Expand
Pathogen Shifts and Changing Cure Rates for Otitis Media and Tonsillopharyngitis
TLDR
Pneumococcal conjugate vaccine use has caused a decrease in the incidence of recurrent and refractory acute otitis media in the United States and a shift in the predominant pathogens, which has implications for optimal antibiotic therapy. Expand
Treatment Options for Streptococcal Pharyngitis
TLDR
Group A β-hemolytic streptococcus resistance to macrolides as a class is a growing problem that should temper their use, and most oral cephalosporins have superior bacteriologic eradication and clinical response compared with narrow-spectrums and broader-spectrum penicillins. Expand
Selecting the Optimal Antibiotic in the Treatment of Group A β-Hemolytic Streptococci Pharyngitis
TLDR
The evidence is examined in order to help the practitioner choose the optimal antibiotic treatment for their patients with group A β-hemolytic streptococcal pharyngitis. Expand
Optimizing the Management of the Main Acute Infections in Pediatric ORL: Tonsillitis, Sinusitis, Otitis media
TLDR
Given that most of these infections progress favorably without antibiotics, the use of these drugs should be avoided unless the child belongs to a high risk group for complications, or symptoms persist or worsen with despite symptomatic treatment. Expand
Evaluation of Clinical Properties and Diagnostic Test Results of Cephalosporin Allergy in Children
TLDR
Cephalosporin allergy has been confirmed in approximately one-fourth of the patients evaluated for suspected cephalic allergy, significantly more common among patients who were older, had immediate reactions, and had taken the drug parenterally. Expand
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References

SHOWING 1-10 OF 111 REFERENCES
Meta-analysis of cephalosporin versus penicillin treatment of group A streptococcal tonsillopharyngitis in children.
TLDR
It is indicated that the likelihood of bacteriologic and clinical failure of GABHS tonsillopharyngitis is significantly less if an oral cephalosporin is prescribed, compared with oral penicillin. Expand
Meta-analysis of cephalosporins versus penicillin for treatment of group A streptococcal tonsillopharyngitis in adults.
  • J. Casey, M. Pichichero
  • Medicine
  • Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
  • 2004
TLDR
The likelihood of bacteriologic and clinical failure in the treatment of GABHS tonsillopharyngitis is 2 times higher for oral penicillin than for oral cephalosporins. Expand
Comparison of oral cephalosporins with penicillin therapy for Group A streptococcal pharyngitis
TLDR
It is concluded that the oral cephalosporins appear to be more effective than penicillin for therapy of Group A streptococcal pharyngitis. Expand
Efficacy of Penicillin vs. Amoxicillin in Children with Group A Beta Hemolytic Streptococcal Tonsillopharyngitis
TLDR
Amoxicillin may be superior to penicillin for bacteriologic and clinical cure of GABHS tonsillopharyngitis and logistic regression analysis was used to adjust for treatment group differences. Expand
Cephalexin and penicillin in the treatment of group A beta-hemolytic streptococcal throat infections.
TLDR
Cephalexin is a more effective drug than penicillin in the treatment of group A beta-hemolytic streptococcal throat infection in children, according to a randomized, double-blind, crossover study conducted from 1981 to 1984. Expand
Comparative study of the effectiveness of cefixime and penicillin V for the treatment of streptococcal pharyngitis in children and adolescents.
TLDR
CFX, once daily, was as safe as and significantly more effective than PEN given 3 times daily for the treatment of Group A beta-hemolytic streptococcal pharyngitis. Expand
A comparison of cephalosporins and penicillins in the treatment of Group A beta‐hemolytic streptococcal pharyngitis: a meta‐analysis supporting the concept of microbial copathogenicity
TLDR
A meta-analysis of 19 studies to examine whether oral cephalosporins were associated with lower failure rates than oral penicillin in the treatment of Group A beta-hemolytic streptococcal pharyngitis found no significant difference between the cep Halosporin and the penicillins with respect to adverse events. Expand
Multicenter comparative trial of cefixime and phenoxymethylpenicillin for group a beta-hemolytic streptococcal tonsillitis
TLDR
A 4-day course of cefixime appears to be an effective treatment for GABHS tonsillitis. Expand
Cefuroxime axetil and penicillin V compared in the treatment of group A beta-hemolytic streptococcal pharyngitis.
TLDR
Cefuroxime axetil is at least as effective as penicillin V in the management of streptococcal pharyngitis and may be more effective in preventing the carrier state. Expand
Is penicillin the appropriate treatment for recurrent tonsillopharyngitis? Results from a comparative randomized blind study of cefuroxime axetil and phenoxymethylpenicillin in children. The Swedish Study Group.
TLDR
Cefuroxime axetil treatment gave a significantly higher bacteriological eradication rate and clinical cure rate than PcV and the patients who experienced bacteriological treatment failure at either the first or second follow-up had the same serotype isolated pre- and post-treatment. Expand
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