Comparison of European and U.S. results for cephalosporin versus penicillin treatment of group A streptococcal tonsillopharyngitis

@article{Pichichero2006ComparisonOE,
  title={Comparison of European and U.S. results for cephalosporin versus penicillin treatment of group A streptococcal tonsillopharyngitis},
  author={M E Pichichero and Janet R. Casey},
  journal={European Journal of Clinical Microbiology and Infectious Diseases},
  year={2006},
  volume={25},
  pages={354-364}
}
  • M. PichicheroJ. Casey
  • Published 31 May 2006
  • Medicine, Biology
  • European Journal of Clinical Microbiology and Infectious Diseases
The outcome of cephalosporin versus penicillin treatment of group A streptococcal tonsillopharyngitis may differ between Europe and the USA. In the present study, Medline, Embase, reference lists, and abstract searches were used to identify randomized, controlled trials of cephalosporin versus penicillin treatment of group A streptococcal (GAS) tonsillopharyngitis. The outcomes of interest were bacteriologic and clinical cure rates from investigations conducted in Europe versus those conducted… 
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22 Citations
Background Citations
7
Methods Citations
1
Results Citations
2

22 Citations

The Importance of Bacteriologic Eradication in the Treatment of Group A Streptococcal Tonsillopharyngitis

The evidence base supporting the selection of cephalosporins in preference to penicillin for treatment of group A β-hemolytic streptococci tonsillopharyngitis is very strong (type A), and these agents have a better tolerability and adherence profile.

The evidence base for cephalosporin superiority over penicillin in streptococcal pharyngitis.

Evaluation of short-term clinical efficacy of 3-day therapy with azithromycin in comparison with 5-day cefcapene-pivoxyl for acute streptococcal tonsillopharyngitis in primary care

  • T. KogaT. Rikimaru K. Matsuo
  • Medicine
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy
  • 2011
The clinical efficacy of a 3-day course with AZM was comparable with that of a 5- day course of CFPN-PI for GAS tonsillopharyngitis, and there was no significant difference in clinical efficacy between the two treatments.

Bacterial eradication rates with shortened courses of 2nd- and 3rd-generation cephalosporins versus 10 days of penicillin for treatment of group A streptococcal tonsillopharyngitis in adults.

Five-day oral cefditoren pivoxil versus 10-day oral amoxicillin for pediatric group A streptococcal pharyngotonsillitis

  • T. OzakiN. Nishimura K. Funahashi
  • Medicine, Biology
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy
  • 2008
Because the efficacy for pediatric group A streptococcus pharyngotonsillitis was similar between oral cefditoren-pivoxil for 5 days and amoxicillin for 10 days, the shorter treatment period may make the former regimen preferable.

Pathogen Shifts and Changing Cure Rates for Otitis Media and Tonsillopharyngitis

Pneumococcal conjugate vaccine use has caused a decrease in the incidence of recurrent and refractory acute otitis media in the United States and a shift in the predominant pathogens, which has implications for optimal antibiotic therapy.

Selecting the Optimal Antibiotic in the Treatment of Group A β-Hemolytic Streptococci Pharyngitis

The evidence is examined in order to help the practitioner choose the optimal antibiotic treatment for their patients with group A β-hemolytic streptococcal pharyngitis.

Optimizing the Management of the Main Acute Infections in Pediatric ORL: Tonsillitis, Sinusitis, Otitis media

Evaluation of Clinical Properties and Diagnostic Test Results of Cephalosporin Allergy in Children

Cephalosporin allergy has been confirmed in approximately one-fourth of the patients evaluated for suspected cephalic allergy, significantly more common among patients who were older, had immediate reactions, and had taken the drug parenterally.

Cefdinir: an oral cephalosporin for the treatment of respiratory tract infections and skin and skin structure infections

Cefdinir continues to represent an important cephalosporin option for the treatment of adult, adolescent and pediatric patients with mild or moderate respiratory tract or cutaneous infections, especially in areas with elevated rates of β-lactamase production in Haemophilus influenzae and where resistance to other commonly used agents has emerged.

References

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It is indicated that the likelihood of bacteriologic and clinical failure of GABHS tonsillopharyngitis is significantly less if an oral cephalosporin is prescribed, compared with oral penicillin.

Meta-analysis of cephalosporins versus penicillin for treatment of group A streptococcal tonsillopharyngitis in adults.

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  • Medicine, Biology
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The likelihood of bacteriologic and clinical failure in the treatment of GABHS tonsillopharyngitis is 2 times higher for oral penicillin than for oral cephalosporins.

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