Comparison of DNA damage photoinduced by ketoprofen, fenofibric acid and benzophenone via electron and energy transfer.

@article{Lhiaubet2001ComparisonOD,
  title={Comparison of DNA damage photoinduced by ketoprofen, fenofibric acid and benzophenone via electron and energy transfer.},
  author={V Lhiaubet and Nicole Paillous and Nadia Chouini-Lalanne},
  journal={Photochemistry and photobiology},
  year={2001},
  volume={74 5},
  pages={670-8}
}
Ketoprofen (KP) and fenofibrate, respectively, anti-inflammatory and hypolipidemiant agents, promote anormal photosensitivity in patients and may induce photoallergic cross-reactions correlated to their benzophenone-like structure. Here, their ability to photosensitize the degradation of biological targets was particularly investigated in DNA. The photosensitization of DNA damage by KP and fenofibric acid (FB), the main metabolite of fenofibrate, and their parent compound, benzophenone (BZ… CONTINUE READING