Comparison of Cannabinoid CB1 Receptor Binding in Adolescent and Adult Rats: A Positron Emission Tomography Study Using [18F]MK-9470

@inproceedings{Verdurand2011ComparisonOC,
  title={Comparison of Cannabinoid CB1 Receptor Binding in Adolescent and Adult Rats: A Positron Emission Tomography Study Using [18F]MK-9470},
  author={Mathieu Verdurand and Vu Quoc Huy Nguyen and Daniela Stark and David Zahra and M. C. Gregoire and Ivan D. Greguric and Katerina Zavitsanou},
  booktitle={International journal of molecular imaging},
  year={2011}
}
Despite the important role of cannabinoid CB(1) receptors (CB(1)R) in brain development, little is known about their status during adolescence, a critical period for both the development of psychosis and for initiation to substance abuse. In the present study, we assessed the ontogeny of CB(1)R in adolescent and adult rats in vivo using positron emission tomography with [(18)F]MK-9470. Analysis of covariance (ANCOVA) to control for body weight that would potentially influence [(18)F]MK-9470… CONTINUE READING
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