Comparison of BISAP, Ranson's, APACHE-II, and CTSI Scores in Predicting Organ Failure, Complications, and Mortality in Acute Pancreatitis

  title={Comparison of BISAP, Ranson's, APACHE-II, and CTSI Scores in Predicting Organ Failure, Complications, and Mortality in Acute Pancreatitis},
  author={Georgios I. Papachristou and Venkata Muddana and Dhiraj Yadav and Michael R. O'Connell and Michael K. Sanders and Adam A Slivka and David C. Whitcomb},
  journal={The American Journal of Gastroenterology},
OBJECTIVES:Identification of patients at risk for severe disease early in the course of acute pancreatitis (AP) is an important step to guiding management and improving outcomes. [] Key Method The BISAP and APACHE-II scores were calculated using data from the first 24 h from admission. Predictive accuracy of the scoring systems was measured by the area under the receiver-operating curve (AUC).RESULTS:There were 185 patients with AP (mean age 51.7, 51% males), of which 73% underwent contrast-enhanced CT scan…

Comparison of Ranson, Glasgow, MOSS, SIRS, BISAP, APACHE-II, CTSI Scores, IL-6, CRP, and Procalcitonin in Predicting Severity, Organ Failure, Pancreatic Necrosis, and Mortality in Acute Pancreatitis

CRP and IL-6 have shown a promising result in early detection of severity and pancreatic necrosis whereas APACHE-II and Ranson score in predicting AP related mortality in this study.

Computed Tomography Severity Index vs. Other Indices in the Prediction of Severity and Mortality in Acute Pancreatitis: A Predictive Accuracy Meta-analysis

Though APACHE II is the most accurate predictor of mortality, CTSI is a good predictor of both mortality and AP severity, which should be used more often in routine clinical practice.

Predicting morbidity and mortality in acute pancreatitis in an Indian population: a comparative study of the BISAP score, Ranson’s score and CT severity index

The BISAP score represents a simple way of identifying, within 24 hours of presentation, patients at greater risk of dying and the development of intermediate markers of severity, in a tertiary care centre in east central India.

Comparative evaluation of BISAP score and computed tomography severity index as a predictor for severity of acute pancreatitis

BISAP score is better predictor of severity and mortality in acute pancreatitis and can safely be utilized to predict severity of acute Pancreatitis in situations where use of CT is limited due to cost factor or availability, especially in rural areas.

Early Changes in Blood Urea Nitrogen (BUN) Can Predict Mortality in Acute Pancreatitis: Comparative Study between BISAP Score, APACHE-II, and Other Laboratory Markers—A Prospective Observational Study

Rise in BUN at 24 hours is a quick and reliable test in predicting mortality and persisting multiorgan failure in AP patients, according to area-under-the-curve receiver-operating characteristics (AUC) analysis and sensitivity and specificity tests.

Comparative Study of BISAP and Ranson ’ s Score in Assessing the Severity of Acute Pancreatitis

Blood urea emerged as a powerful predictor of organ failure and Ranson’s and BISAP scores showed concordance on statistical analysis and B ISAPs scoring system can be used to predict accurately, the severity and organ failure within hours of admission.

Bisap Score and Ranson’s Score in Predicting Severity of Acute Pancreatitis: A Comparative Study

Ranson’s score had a higher sensitivity and BISAP had higher specificity in the prediction of severe pancreatitis, compared to both in predicting the severity of acute pancreatitis.

Comparison of scoring systems in predicting the severity of acute pancreatitis.

Various scoring systems showed similar predictive accuracy for severity of AP, however, APACHE-II demonstrated the highest accuracy for prediction of severe AP, and no statistically significant pairwise differences were observed between APAC HE-II and the other scoring systems, including CRP24.



A Prospective Evaluation of the Bedside Index for Severity in Acute Pancreatitis Score in Assessing Mortality and Intermediate Markers of Severity in Acute Pancreatitis

The BISAP score represents a simple way to identify patients at risk of increased mortality and the development of intermediate markers of severity within 24 h of presentation and can be utilized to improve clinical care and facilitate enrollment in clinical trials.

Obesity Increases the Severity of Acute Pancreatitis: Performance of APACHE-O Score and Correlation with the Inflammatory Response

The study results suggest that obesity increases the severity of AP by amplifying the immune response to injury and is an independent risk for SAP.

APACHE system is better than Ranson system in the prediction of severity of acute pancreatitis.

The APACHE-II scoring system is more accurate than the Ranson scoring system of the prediction of severity in acute pancreatitis, and addition of obesity score does not significantly improve the predictive accuracy of the APAC HE-II system in the local population with a low prevalence of obesity.

The early prediction of mortality in acute pancreatitis: a large population-based study

The BISAP is a simple and accurate method for the early identification of patients at increased risk for in-hospital mortality in acute pancreatitis.

Prediction of severe acute pancreatitis: current knowledge and novel insights.

Several cytokines have been found to play a critical role in the pathogenesis of AP by driving the subsequent inflammatory response, to include tumor necrosis factor-alpha (TNF-alpha), Interleukin-1, IL-1), IL-6 and monocyte chemotactic protein-1 (MCP-1).

Acute pancreatitis: value of CT in establishing prognosis.

A CT severity index, based on a combination of peripancreatic inflammation, phlegmon, and degree of pancreatic necrosis as seen at initial CT study, was developed and showed clear trends in patients who initially had or developed more than 30% necrosis.

A clinically based classification system for acute pancreatitis. Summary of the International Symposium on Acute Pancreatitis, Atlanta, Ga, September 11 through 13, 1992.

Unanimous consensus on a series of definitions and a clinically based classification system for acute pancreatitis was achieved by a diverse group of 40 international authorities from six medical disciplines and 15 countries, of value to practicing clinicians in the care of individual patients and to academicians seeking to compare interinstitutional data.

Severe acute pancreatitis.

Important clinical guidelines, randomized controlled trials (RCTs), meta-analyses, large case series from centers of excellence, and consensus conference reports form the basis of this article.

Risk and markers of severe acute pancreatitis.