Comparison of 4,4'-diaminodiphenylsulfone and its thymolated derivative in experimental tuberculosis in guinea pigs.

@article{Karlson1958ComparisonO4,
  title={Comparison of 4,4'-diaminodiphenylsulfone and its thymolated derivative in experimental tuberculosis in guinea pigs.},
  author={Alfred G. Karlson},
  journal={Diseases of the chest},
  year={1958},
  volume={33 6},
  pages={
          600-6
        }
}
SUMMARY AND CONCLUSIONS Each of 36 guinea pigs was infected intraperitoneally with virulent tubercle bacilli. After 16 days, six were killed and found to have tuberculous lesions. On the same day, the remaining animals were divided into three groups of 10 animals each, namely controls, those treated with 4,4′-diaminodiphenylsulfone (DDS), and those treated with DDS-thymol. Treatment continued for 116 days, at which time all survivors were killed. Six controls had died by this time. All controls… CONTINUE READING

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