Comparison of 2 treatment strategies for depressed inpatients: imipramine and lithium addition or mirtazapine and lithium addition.

@article{Bruijn1998ComparisonO2,
  title={Comparison of 2 treatment strategies for depressed inpatients: imipramine and lithium addition or mirtazapine and lithium addition.},
  author={Jacques Bruijn and Peter Moleman and Paul G. H. Mulder and Walter W. van den Broek},
  journal={The Journal of clinical psychiatry},
  year={1998},
  volume={59 12},
  pages={657-63}
}
BACKGROUND The purpose of this study was to compare the overall effectiveness of 2 treatment strategies for inpatients with severe major depressive episode (DSM-III-R): (1) mirtazapine (phase 1) and subsequent lithium addition (phase 2) or (2) imipramine (phase 1) and subsequent lithium addition (phase 2). We previously reported the results of phase 1. METHOD In phase 1, patients were randomly assigned to treatment with either mirtazapine or imipramine, and doses were adjusted to obtain… CONTINUE READING

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