Comparison of [125I]Iodolysergic Acid Diethylamide Binding in Human Frontal Cortex and Platelet Tissue

@article{Elliott1989ComparisonO,
  title={Comparison of [125I]Iodolysergic Acid Diethylamide Binding in Human Frontal Cortex and Platelet Tissue},
  author={J. Martin Elliott and Aysha S Kent},
  journal={Journal of Neurochemistry},
  year={1989},
  volume={53}
}
Abstract: The human platelet contains a functional 5‐hy‐droxytryptamine (5‐HT) receptor that appears to resemble the 5‐HT2 subtype. In this study, we have used the iodinated derivative [I25I]iodolysergic acid diethylamide ([I25I]iodoLSD) in an attempt to label 5‐HT receptors in human platelet and frontal cortex membranes under identical assay conditions to compare the sites labelled in these two tissues. In human frontal cortex, [125I]iodoLSD labelled a single high‐affinity site (KD= 0.35 ± 0… 
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