Comparison of (+)-(11)C-McN5652 and (11)C-DASB as serotonin transporter radioligands under various experimental conditions.

@article{Szabo2002ComparisonO,
  title={Comparison of (+)-(11)C-McN5652 and (11)C-DASB as serotonin transporter radioligands under various experimental conditions.},
  author={Zsolt Szabo and Una D. McCann and Alan A. Wilson and Ursula A Scheffel and Taofeek K Owonikoko and William B Mathews and Hayden T. Ravert and John Hilton and Robert F. Dannals and George A. Ricaurte},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year={2002},
  volume={43 5},
  pages={678-92}
}
UNLABELLED There has been considerable interest in the development of a PET radioligand selective for the serotonin (5-hydroxytryptamine [5-HT]) transporter (SERT) that can be used to image 5-HT neurons in the living human brain. The most widely used SERT radiotracer to date, trans-1,2,3,5,6,10-beta-hexahydro-6-[4-(methylthio)phenyl[pyrrolo-[2,1-a]isoquinoline ((+)-(11)C-McN5652), has been successful in this regard but may have some limitations. Recently, another promising SERT radiotracer, 3… CONTINUE READING
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