Comparison in humans of the potency and pharmacokinetics of intravenously injected cocaethylene and cocaine

@article{PrezReyes2005ComparisonIH,
  title={Comparison in humans of the potency and pharmacokinetics of intravenously injected cocaethylene and cocaine},
  author={M. P{\'e}rez-Reyes and A. Jeffcoat and M. Myers and K. Sihler and C. Cook},
  journal={Psychopharmacology},
  year={2005},
  volume={116},
  pages={428-432}
}
Cocaethylene (the ethyl ester of benzoylecgonine) is a product of the interaction between ethanol and cocaine. The results of preclinical studies and of a pilot clinical study have shown cocaethylene to produce pharmacologic effects similar to those of cocaine. However, no information is available concerning the potency and pharmacokinetics of cocaethylene in comparison to those of cocaine in humans. We report the results of a single-blind, crossover study in which six male, healthy, paid… Expand
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