Comparison by flow cytometry of immune changes induced in human monocyte-derived dendritic cells upon infection with dengue 2 live-attenuated vaccine or 16681 parental strain.

@article{Sanchez2006ComparisonBF,
  title={Comparison by flow cytometry of immune changes induced in human monocyte-derived dendritic cells upon infection with dengue 2 live-attenuated vaccine or 16681 parental strain.},
  author={Violette Sanchez and Catherine Hessler and Aymeric DeMonfort and Jean -Marie Lang and Bruno Guy},
  journal={FEMS immunology and medical microbiology},
  year={2006},
  volume={46 1},
  pages={113-23}
}
Dengue is an important threat for world-wide public health. Different vaccines are under development, which are currently assessed using a battery of in vitro and in vivo assays before moving on to humans. It is also important to assess vaccine characteristics on human primary cells; among them, dendritic cells, the most efficient antigen-presenting cells, are the first targets of dengue virus infection. In this study, we used flow cytometry to compare the consequences of such an infection by… CONTINUE READING

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