Comparison between theprotective effects ofmycobacterial 65-kD heatshockprotein andovomucoid inpristane-induced arthritis: relationship withagalactosyl IgG

@inproceedings{Ghoraishian1993ComparisonBT,
  title={Comparison between theprotective effects ofmycobacterial 65-kD heatshockprotein andovomucoid inpristane-induced arthritis: relationship withagalactosyl IgG},
  author={M. Ghoraishian},
  year={1993}
}
SUMMARY TheIgGofpatients withrheumatoid arthritis andmicewithpristane induced arthritis (PIA) tends to lack theterminal galactose normally ontheconserved N-acetylglucosamine linked fIl-2 tomannose inIgG.Theterminal N-acetylglucosamine (GlcNAc) residues ofoligosaccharides onagalactosyl IgG maybeanimportant component oftheaction ofthese glycoforms. Here,administration of ovomucoid, aglycoprotein rich interminal GlcNAc, before pristane injection wasfound toreduce theincidence ofPIA.Thisobservation… CONTINUE READING

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