Comparison between solution-phase stability and gas-phase kinetic stability of oligodeoxynucleotide duplexes.

@article{Gabelica2001ComparisonBS,
  title={Comparison between solution-phase stability and gas-phase kinetic stability of oligodeoxynucleotide duplexes.},
  author={Val{\'e}rie Gabelica and Edwin de Pauw},
  journal={Journal of mass spectrometry : JMS},
  year={2001},
  volume={36 4},
  pages={397-402}
}
The relative kinetic stabilities of different 16-mer oligonucleotide duplexes were investigated by source collision-induced dissociation (CID) in a heated capillary electrospray ion source. They were compared with the relative stabilities in solution obtained by thermal denaturation monitored by UV spectrophotometry. The results clearly show that both hydrogen bonding and base stacking interactions that are present in solution are maintained in the gas phase. This suggests that the electrospray… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-9 of 9 references

Int

CA Schalley
J. Mass Spectrom. • 2000
View 2 Excerpts

Rapid Commun

V Gabelica, F Rosu, C Houssier, E De Pauw
Mass Spectrom. • 2000

Biophys

J Gao, Q Wu, +3 authors GM Whitesides
J. • 1999

Chem

P Hobza, J Sponer
Rev. • 1999

J

SG Penn, F He, CB Lebrilla
Phys. Chem. B • 1998

Mass Spectrom

JA Loo
Rev. • 1997

Curr

DH Turner
Opin. Struct. Biol. • 1996

Supramolecular chemistry, VCH

Lehn J-M
Verlagesellschaft • 1995

In Biophysical Chemistry

CR Cantor, PR Shimmel
Part III: The Behavior of Biological Macromolecules. Freeman and Company. San Fransisco. • 1980

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