Comparison between self-reported facial flushing after alcohol consumption and ALDH2 Glu504Lys polymorphism for risk of upper aerodigestive tract cancer in a Japanese population.

@article{Oze2010ComparisonBS,
  title={Comparison between self-reported facial flushing after alcohol consumption and ALDH2 Glu504Lys polymorphism for risk of upper aerodigestive tract cancer in a Japanese population.},
  author={Isao Oze and Keitaro Matsuo and Satoyo Hosono and Hidemi Ito and Takakazu Kawase and Miki Watanabe and Takeshi Suzuki and Shunzo Hatooka and Yasushi Yatabe and Yasuhisa Hasegawa and Masayuki Shinoda and Kazuo Tajima and Hideo Tanaka},
  journal={Cancer science},
  year={2010},
  volume={101 8},
  pages={1875-80}
}
Some Japanese exhibit facial flushing after drinking alcohol. Facial flushing was considered to be caused by acetaldehydemia. The concentration of blood acetaldehyde was concerned with the catalytic activity of acetaldehyde dehydrogenase (ALDH). Acetaldehyde dehydrogenase (ALDH)-2 polymorphism (rs671, Glu504Lys) was known to be associated with upper… CONTINUE READING