Comparison between plethysmometer and micrometer methods to measure acute paw oedema for screening anti-inflammatory activity in mice

@article{Sharma2004ComparisonBP,
  title={Comparison between plethysmometer and micrometer methods to measure acute paw oedema for screening anti-inflammatory activity in mice},
  author={Jagdish Narain Sharma and Awatef M. Samud and Mohd. Zaini Asmawi},
  journal={InflammoPharmacology},
  year={2004},
  volume={12},
  pages={89-94}
}
The present study was undertaken to evaluate the sensitivity of the plethysmometer and micrometer, which are the most commonly employed methods to measure the paw oedema for screening anti-inflammatory agents. Acute paw swelling was induced by s.c. injection of 0.02 ml carrageenan in mice. The maximum paw oedema (59.4%) was found to be at 3.5 h after… CONTINUE READING