Comparison between mefenamic acid and danazol in the treatment of established menorrhagia.

@article{Dockeray1989ComparisonBM,
  title={Comparison between mefenamic acid and danazol in the treatment of established menorrhagia.},
  author={C J Dockeray and Brian L Sheppard and John Bonnar},
  journal={British journal of obstetrics and gynaecology},
  year={1989},
  volume={96 7},
  pages={840-4}
}
Forty women with established menorrhagia were treated with either mefenamic acid (500 mg thrice daily for 3-5 days in two cycles) or danazol (100 mg twice daily for 60 days) in an open parallel group randomized study. Mefenamic acid reduced mean menstrual blood loss from 160 ml to 127 ml (20%, P less than 0.01). Danazol reduced mean menstrual loss from 163 ml to 65 ml (60%, P less than 0.001). The percentage reduction in menstrual blood loss was significantly greater in the danazol group than… CONTINUE READING

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