Comparison between basal and apical dendritic spines in estrogen-induced rapid spinogenesis of CA1 principal neurons in the adult hippocampus.

@article{Murakami2006ComparisonBB,
  title={Comparison between basal and apical dendritic spines in estrogen-induced rapid spinogenesis of CA1 principal neurons in the adult hippocampus.},
  author={Gen Murakami and Tomokazu Tsurugizawa and Yusuke Hatanaka and Yoshimasa Komatsuzaki and Nobuaki Tanabe and Hideo Mukai and Yasushi Hojo and Shiro A J Kominami and Takeshi Yamazaki and Tetsuya Kimoto and S Kawato},
  journal={Biochemical and biophysical research communications},
  year={2006},
  volume={351 2},
  pages={
          553-8
        }
}
Modulation of hippocampal synaptic plasticity by estrogen has been attracting much attention. Here, we demonstrated the rapid effect of 17beta-estradiol on the density and morphology of spines in the stratum oriens (s.o., basal side) and in the stratum lacunosum-moleculare (s.l.m., apical side) by imaging Lucifer Yellow-injected CA1 neurons in adult male rat hippocampal slices, because spines in s.o. and s.l.m. have been poorly understood as compared with spines in the stratum radiatum. The… CONTINUE READING

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