Comparison and interaction of low dose felodipine and enalapril in the treatment of essential hypertension in elderly subjects.

@article{Morgan1992ComparisonAI,
  title={Comparison and interaction of low dose felodipine and enalapril in the treatment of essential hypertension in elderly subjects.},
  author={Trefor Owen Morgan and Alice M Anderson and Emma Jones},
  journal={American journal of hypertension},
  year={1992},
  volume={5 4 Pt 1},
  pages={238-43}
}
The antihypertensive effect and tolerance of the combined low doses of felodipine and enalapril (5 + 5 mg daily) were compared with those of either drug at a higher dose level (10 mg daily). Our double-blind, three-way crossover study (balanced Latin square design) involved 36 elderly subjects (mean age 67 +/- 6 years) with essential hypertension. After a 4-week placebo run-in phase the subjects were randomized to the active treatment periods, starting with 5 mg felodipine plus 5 mg enalapril… CONTINUE READING

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