Comparison and characterization of multiple biomaterial conduits for peripheral nerve repair.

  title={Comparison and characterization of multiple biomaterial conduits for peripheral nerve repair.},
  author={William T Daly and Andrew M Knight and Huan Wang and Ralph de Boer and Guilherme Giusti and Mahrokh Dadsetan and Robert J Spinner and Michael J. Yaszemski and Anthony J Windebank},
  volume={34 34},
Four biomaterial tubes, poly(lactic-co-glycolic acid) (PLGA), poly(caprolactone fumarate) (PCLF), a neutral oligo[(polyethylene glycol) fumarate] (OPF) hydrogel or a positively charged oligo[(polyethylene glycol) fumarate] (OPF(+)) hydrogel with a PCLF sleeve, have previously been shown to have benefits for nerve repair. However, no direct comparison to identify the optimal material have been made. Herein, these nerve tubes were implanted in a rat sciatic nerve model and nerve regeneration was… CONTINUE READING
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