Comparing the scoring mechanisms of p16INK4a immunohistochemistry based on independent nucleic stains and independent cytoplasmic stains in distinguishing between endocervical and endometrial adenocarcinomas in a tissue microarray study

@article{Kok2009ComparingTS,
  title={Comparing the scoring mechanisms of p16INK4a immunohistochemistry based on independent nucleic stains and independent cytoplasmic stains in distinguishing between endocervical and endometrial adenocarcinomas in a tissue microarray study},
  author={L Kok and M J Lee and Yeu-Sheng Tyan and Tina S. Wu and Ya-Wen Cheng and M Kung and P Wang and C Han},
  journal={Archives of Gynecology and Obstetrics},
  year={2009},
  volume={281},
  pages={293-300}
}
Endocervical adenocarcinomas (ECAs) and endometrial adenocarcinomas (EMAs) are malignancies that affect the uterus; however, their biological behaviors are quite different. This distinction has clinical significance because the appropriate therapy may depend on the site of tumor origin. The purpose of this study is to evaluate two different scoring mechanisms of p16INK4a immunohistochemical (IHC) stain in distinguishing between primary ECAs and EMAs. A tissue microarray (TMA) was constructed… CONTINUE READING
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Cervical and vaginal cancer, chap 34

  • MA Bidus, JC Elkas
  • Berek JS (ed) Berek & Novak’s gynecology,
  • 2007
1 Excerpt

Uterine cancer, chap 33

  • JR Lurain
  • Berek JS (ed) Berek & Novak’s gynecology,
  • 2007
1 Excerpt

Immunohistochemical expression of p 53 , p 24 , p 16 , and cyclin D 1 in super W cial bladder cancer . A tissue microarray study

  • FR VallmanyaLlena, A LabordaRodríguez, J LloretaTrull, R CortadellasAngel, J PlacerSantos, A MasGelabert
  • Actas Urol Esp
  • 2006

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