Comparing the outcome between multicentric and multifocal breast cancer: what is the impact on survival, and is there a role for guideline-adherent adjuvant therapy? A retrospective multicenter cohort study of 8,935 patients

@article{Wolters2013ComparingTO,
  title={Comparing the outcome between multicentric and multifocal breast cancer: what is the impact on survival, and is there a role for guideline-adherent adjuvant therapy? A retrospective multicenter cohort study of 8,935 patients},
  author={Regine Wolters and Achim Woeckel and Wolfgang Janni and Igor Novopashenny and Florian Ebner and Rolf Kreienberg and Manfred B. Wischnewsky and Lukas Schwentner},
  journal={Breast Cancer Research and Treatment},
  year={2013},
  volume={142},
  pages={579-590}
}
Multifocal (MF) and multicentric (MC) breast cancers have been comprehensively studied, and their outcomes have been compared with unifocal (UF) tumors. We attempted to answer the following questions: (1) Does MF/MC presentation influence the outcome concerning BC mortality?, (2) Is there an impact of guideline-adherent adjuvant treatment in these BC subtypes?, and (3)What is the influence of guideline violations concerning surgery (breast-conserving surgery versus mastectomy) on the survival… CONTINUE READING