Comparing the neurocognitive effects of 40 h sustained wakefulness in patients with untreated OSA and healthy controls.

@article{Wong2008ComparingTN,
  title={Comparing the neurocognitive effects of 40 h sustained wakefulness in patients with untreated OSA and healthy controls.},
  author={Keith K H Wong and Nathaniel S Marshall and Ronald R Grunstein and Michael J Dodd and Naomi Louise Rogers},
  journal={Journal of sleep research},
  year={2008},
  volume={17 3},
  pages={322-30}
}
We hypothesized that individuals with untreated obstructive sleep apnea (OSA) would exhibit greater vulnerability to sleep deprivation than healthy controls, due to the additional neurobiological 'load' of chronic sleep fragmentation. After baseline sleep with 8 h time in bed, participants remained awake for 40 h. Psychomotor Vigilance Task (PVT, mean slowest 10% 1/RT), AusEd Driving Simulator task (steering and speed deviation), and subjective sleepiness (Karolinska Sleepiness Scale, KSS) were… CONTINUE READING

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