Comparing the human and chimpanzee genomes: Searching for needles in a haystack

@article{Varki2005ComparingTH,
  title={Comparing the human and chimpanzee genomes: Searching for needles in a haystack},
  author={A. Varki and T. K. Altheide},
  journal={Genome Research},
  year={2005},
  volume={15},
  pages={1746-1758}
}
The chimpanzee genome sequence is a long-awaited milestone, providing opportunities to explore primate evolution and genetic contributions to human physiology and disease. Humans and chimpanzees shared a common ancestor approximately 5-7 million years ago (Mya). The difference between the two genomes is actually not approximately 1%, but approximately 4%--comprising approximately 35 million single nucleotide differences and approximately 90 Mb of insertions and deletions. The challenge is to… Expand
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