Comparing the effects of inorganic nitrate and allopurinol in renovascular complications of metabolic syndrome in rats: role of nitric oxide and uric acid

@inproceedings{Essawy2014ComparingTE,
  title={Comparing the effects of inorganic nitrate and allopurinol in renovascular complications of metabolic syndrome in rats: role of nitric oxide and uric acid},
  author={Soha S. Essawy and Khaled A. Abdel-Sater and Amani A. Elbaz},
  booktitle={Archives of medical science : AMS},
  year={2014}
}
INTRODUCTION The epidemic of metabolic syndrome is increasing worldwide and correlates with elevation in serum uric acid and marked increase in total fructose intake. Fructose raises uric acid and the latter inhibits nitric oxide bioavailability. We hypothesized that fructose-induced hyperuricemia may have a pathogenic role in metabolic syndrome and treatment of hyperuricemia or increased nitric oxide may improve it. MATERIAL AND METHODS Two experiments were performed. Male Sprague-Dawley… CONTINUE READING

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