Comparing the benefits of screening for breast cancer and lung cancer using a novel natural history model

@article{Lin2011ComparingTB,
  title={Comparing the benefits of screening for breast cancer and lung cancer using a novel natural history model},
  author={Ray Shih-Jui Lin and Sylvia K Plevritis},
  journal={Cancer Causes & Control},
  year={2011},
  volume={23},
  pages={175-185}
}
To estimate the impact of early detection of cancer, knowledge of how quickly primary tumors grow and at what size they shed lethal metastases is critical. We developed a natural history model of cancer to estimate the probability of disease-specific cure as a function of tumor size, the tumor volume doubling time (TVDT), and disease-specific mortality reduction achievable by screening. The model was applied to non-small-cell lung carcinoma (NSCLC) and invasive ductal carcinoma (IDC… CONTINUE READING