Comparing positron emission tomography imaging and cerebrospinal fluid measurements of β-amyloid.

@article{Landau2013ComparingPE,
  title={Comparing positron emission tomography imaging and cerebrospinal fluid measurements of β-amyloid.},
  author={Susan M. Landau and Ming Lu and Abhinay D. Joshi and Michael J. Pontecorvo and Mark A. Mintun and John Q. Trojanowski and Leslie M. Shaw and William J. Jagust},
  journal={Annals of neurology},
  year={2013},
  volume={74 6},
  pages={826-36}
}
OBJECTIVE We examined agreement and disagreement between 2 biomarkers of β-amyloid (Aβ) deposition (amyloid positron emission tomography [PET] and cerebrospinal fluid [CSF] Aβ1-42 ) in normal aging and dementia in a large multicenter study. METHODS Concurrently acquired florbetapir PET and CSF Aβ were measured in cognitively normal, mild cognitive impairment (MCI), and Alzheimer's disease participants (n = 374) from the Alzheimer's Disease Neuroimaging Initiative. We also compared A… CONTINUE READING
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