Comparing ectopic bone growth induced by rhBMP-2 on an absorbable collagen sponge in rat and rabbit models.

@article{Hsu2006ComparingEB,
  title={Comparing ectopic bone growth induced by rhBMP-2 on an absorbable collagen sponge in rat and rabbit models.},
  author={H P Hsu and John M Zanella and Steve M Peckham and Myron Spector},
  journal={Journal of orthopaedic research : official publication of the Orthopaedic Research Society},
  year={2006},
  volume={24 8},
  pages={1660-9}
}
Recombinant human Bone Morphogenetic Protein-2 (rhBMP-2) is currently employed as an autograft replacement for spinal fusion. The morphogen is incorporated onto its carrier, an absorbable collagen sponge (ACS), in the operating room. Although the effectiveness of the rhBMP-2/ACS implant in stimulating bone formation in human subjects has now been well… CONTINUE READING