Comparing HMG-CoA reductase inhibitors.

  title={Comparing HMG-CoA reductase inhibitors.},
  author={Peter Jh Jones},
  journal={Clinical cardiology},
  volume={26 1 Suppl 1},
The statins have proved to be some of the most potent therapies for reducing elevated low-density lipoprotein (LDL) cholesterol and lessening the risk of coronary heart disease (CHD) and related events. Nonetheless, there are still questions about the clinical relevance of individual drug characteristics, such as chemical derivation, solubility properties, and metabolic route, in terms of tolerability or therapeutic benefit. At the same time, no clear explanation has emerged for the… CONTINUE READING