Comparing Apples and Oranges?: Next Generation Sequencing and Its Impact on Microbiome Analysis

@inproceedings{Clooney2016ComparingAA,
  title={Comparing Apples and Oranges?: Next Generation Sequencing and Its Impact on Microbiome Analysis},
  author={Adam G. Clooney and Fiona Fouhy and Roy D. Sleator and Aisling O’ Driscoll and Catherine Stanton and Paul D Cotter and Marcus J. Claesson and Bryan A. White},
  booktitle={PloS one},
  year={2016}
}
Rapid advancements in sequencing technologies along with falling costs present widespread opportunities for microbiome studies across a vast and diverse array of environments. These impressive technological developments have been accompanied by a considerable growth in the number of methodological variables, including sampling, storage, DNA extraction, primer pairs, sequencing technology, chemistry version, read length, insert size, and analysis pipelines, amongst others. This increase in… CONTINUE READING