Comparative virulence of NAD-dependent and NAD-independent Actinobacillus pleuropneumoniae strains.

@article{Dom1992ComparativeVO,
  title={Comparative virulence of NAD-dependent and NAD-independent Actinobacillus pleuropneumoniae strains.},
  author={P P Dom and Freddy Haesebrouck},
  journal={Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B},
  year={1992},
  volume={39 4},
  pages={303-6}
}
The virulence of a NAD-independent Actinobacillus pleuropneumoniae serotype 2 strain and NAD-dependent serotype 2, 3 and 9 strains was compared under experimental conditions. Hysterectomy-derived piglets were inoculated endobronchially with 50-500 cfu of these strains. All 23 piglets inoculated with the NAD-dependent strains developed acute disease within 12 hours post inoculation. Twenty-two of these piglets died within 24 hours after the first clinical signs. Three of nine piglets inoculated… CONTINUE READING