Comparative trial of two enterostomy sealants.


The mechanism of blistering is obscure. Although its onset in relation to high-dose frusemide is extremely suggestive, the blistering tendency subsides in weeks or months, irrespective of whether large doses of frusemide are continued or not. It is tempting to speculate that frusemide interferes with tissue metabolism in the region of the dermal-epidermal junction in a manner that depends on light exposure, inducing what is clinically an acquired form of epidermolysis bullosa.

Cite this paper

@article{Evans1976ComparativeTO, title={Comparative trial of two enterostomy sealants.}, author={Gaynor Evans and Roger A Wood and Leslie E. Hughes}, journal={British medical journal}, year={1976}, volume={1 6024}, pages={1510} }