Comparative trial of single-dose versus twice-daily sisomicin in bacteriuric patients.

@article{Klastersky1977ComparativeTO,
  title={Comparative trial of single-dose versus twice-daily sisomicin in bacteriuric patients.},
  author={Jean A. Klastersky and Jay M. Prevost and F. Meunier-Carpentier and D. Daneau and Mich{\`e}le G{\'e}rard},
  journal={Journal of clinical pharmacology},
  year={1977},
  volume={17 8-9},
  pages={520-8}
}
Sisomicin was administered as a single daily intramuscular injection (160 mg) or as two daily injections (80 mg) to 50 patients with bacteriuria superimposed on chronic urologic diseases in a randomized controlled fashion. The administration of two daily doses was significantly more effective (P less than 0.01) in achieving cure than the injection of a single daily dose. The renal function, as expressed by creatinine clearance, became impaired significantly more often (P less than 0.05) in the… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.

Similar Papers

Loading similar papers…