Comparative trial of prednisone plus aspirin versus aspirin alone in the treatment of anticardiolipin antibody-positive obstetric patients.

@article{Silver1993ComparativeTO,
  title={Comparative trial of prednisone plus aspirin versus aspirin alone in the treatment of anticardiolipin antibody-positive obstetric patients.},
  author={Richard K. Silver and Scott N MacGregor and John S. Sholl and Jim Hobart and Mark G Neerhof and Ann B. Ragin},
  journal={American journal of obstetrics and gynecology},
  year={1993},
  volume={169 6},
  pages={1411-7}
}
OBJECTIVE We compared the use of aspirin alone with combined therapy (prednisone plus aspirin) in antiphospholipid antibody-positive obstetric patients with prior adverse pregnancy outcome. STUDY DESIGN Thirty-nine patients meeting specific laboratory and clinical inclusion criteria were randomized to receive either combined therapy (prednisone plus low-dose aspirin, n = 17) or aspirin alone (n = 22). The daily aspirin dose was 81 mg; prednisone was begun at 20 mg/day and increased or… CONTINUE READING

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